Bioinformatics

Product-stabilized filamentation by human glutamine synthetase allosterically tunes metabolic activity

Product-stabilized filamentation by human glut...

Bioinformatics
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librarian
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Why do some predicted protein structures fold poorly? Benchmarking AlphaFold, ESMFold, and Boltz in maize

Why do some predicted protein structures fold ...

Bioinformatics
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librarian
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Multi-omics time-series analysis in microbiome research: a systematic review

Multi-omics time-series analysis in microbiome...

Bioinformatics
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librarian
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Structural motif search across the protein-universe with Folddisco

Structural motif search across the protein-uni...

Bioinformatics
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librarian
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PIMENTO: A PrIMEr infereNce TOolkit to facilitate large-scale calling of amplicon sequence variants

PIMENTO: A PrIMEr infereNce TOolkit to facilit...

Bioinformatics
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librarian
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A Computational Workflow for Structure-Guided Design of Potent and Selective Kinase Peptide Substrates

A Computational Workflow for Structure-Guided ...

Bioinformatics
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Kenneth Westover
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SpatialMap: A Scalable Deep Learning Method for Cell Typing in Subcellular Spatial Transcriptomics

SpatialMap: A Scalable Deep Learning Method fo...

Bioinformatics
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librarian
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Gain of Function p53 mutant R273H confers distinct methylation profiles and consequent partial or full EMT states to colon tumour

Gain of Function p53 mutant R273H confers dist...

Bioinformatics
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librarian
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SSAlign: Ultrafast and Sensitive Protein Structure Search at Scale

SSAlign: Ultrafast and Sensitive Protein Struc...

Bioinformatics
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Yan Wang
13 views
Transformer-based Deep Learning for Glycan Structure Inference from Tandem Mass Spectrometry

Transformer-based Deep Learning for Glycan Str...

Bioinformatics
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Rudiyanto Gunawan
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OMIDIENT: Multiomics Integration for Cancer by Dirichlet Auto-Encoder Networks

OMIDIENT: Multiomics Integration for Cancer by...

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librarian
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In Situ Inference of Copy Number Variations in Image-Based Spatial Transcriptomics

In Situ Inference of Copy Number Variations in...

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librarian
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Visual-like Template Diffusion: Boosting Single-Sequence Protein Structure Prediction by Adapting Image Diffusion Models

Visual-like Template Diffusion: Boosting Singl...

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Zhen Cui
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Mechanistic modeling and machine learning identifies optimum radiotherapy schedules to prevent treatment-induced metastasis

Mechanistic modeling and machine learning iden...

Bioinformatics
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librarian
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OmniPert: A Deep Learning Foundation Model for Predicting Responses to Genetic and Chemical Perturbations in Single Cancer Cells

OmniPert: A Deep Learning Foundation Model for...

Bioinformatics
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librarian
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Characterization of selective pressures acting on protein sites with Deep Learning

Characterization of selective pressures acting...

Bioinformatics
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librarian
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STELLA: Self-Evolving LLM Agent for Biomedical Research

STELLA: Self-Evolving LLM Agent for Biomedical...

Bioinformatics
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Zaixi Zhang
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GatorST: A Versatile Contrastive Meta-Learning Framework for Spatial Transcriptomic Data Analysis

GatorST: A Versatile Contrastive Meta-Learning...

Bioinformatics
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librarian
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Fold-Conditioned De Novo Binder Design via AlphaFold2-Multimer Hallucination.

Fold-Conditioned De Novo Binder Design via Alp...

Bioinformatics
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librarian
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Modelling punctuated similarity

Modelling punctuated similarity

Bioinformatics
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Sarah Crockford
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A moderated statistical test for detecting shifts in homeolog expression ratios in allopolyploids

A moderated statistical test for detecting shi...

Bioinformatics
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librarian
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DiffMethylTools: a toolbox of the detection, annotation and visualization of differential DNA methylation

DiffMethylTools: a toolbox of the detection, a...

Bioinformatics
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librarian
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PULPO: Pipeline of understanding large-scale patterns of oncogenomic signatures

PULPO: Pipeline of understanding large-scale p...

Bioinformatics
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librarian
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Sequence Analysis of P4-ATPases Reveals the Structural Determinants for the Stable Monomeric P4B-ATPase Phospholipid Transporters.

Sequence Analysis of P4-ATPases Reveals the St...

Bioinformatics
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Jyh-Yeuan Lee
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An Intrinsic-hoc Framework for Heterogeneous Cellular Senescence Elucidation Using Deep Graph Representation Learning and Experimental Validation

An Intrinsic-hoc Framework for Heterogeneous C...

Bioinformatics
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librarian
4 views
Combining AI structure prediction and integrative modelling for nanobody-antigen complexes

Combining AI structure prediction and integrat...

Bioinformatics
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librarian
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NANOME: A Nextflow pipeline for haplotype-aware allele-specific consensus DNA methylation detection by nanopore long-read sequencing

NANOME: A Nextflow pipeline for haplotype-awar...

Bioinformatics
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librarian
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OmniCorr: An R-package for visualizing putative host-microbiota interactions using multi-omics data

OmniCorr: An R-package for visualizing putativ...

Bioinformatics
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librarian
2 views
Rapid and Reproducible Multimodal Biological Foundation Model Development with AIDO.ModelGenerator

Rapid and Reproducible Multimodal Biological F...

Bioinformatics
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librarian
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Uncertainty-Aware Discrete Diffusion Improves Protein Design

Uncertainty-Aware Discrete Diffusion Improves ...

Bioinformatics
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librarian
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Models and Algorithms for Equilibrium Analysis of Mixed-Material Nucleic Acid Systems

Models and Algorithms for Equilibrium Analysis...

Bioinformatics
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librarian
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MarkerMatch: A Proximity-Based Probe-Matching Algorithm for Joint Analysis of Copy-Number Variants from Different Genotyping Arrays

MarkerMatch: A Proximity-Based Probe-Matching ...

Bioinformatics
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Franjo Ivankovic
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