Bioinformatics

Single-cell Transcriptomic Variance Analysis Reveals Intercellular Circadian Desynchrony in the Alzheimer's Affected Human Brain

Single-cell Transcriptomic Variance Analysis R...

Bioinformatics
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Ron Anafi
3 views
Thirty years of Achromobacter ruhlandii evolution reveal pathways to epidemic lineages

Thirty years of Achromobacter ruhlandii evolut...

Bioinformatics
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librarian
3 views
Population-scale interpretation of RNA isoform diversity enabled by Isopedia

Population-scale interpretation of RNA isoform...

Bioinformatics
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librarian
4 views
Compact longitudinal representations derived from mixed-format lifestyle questionnaires outperform static text-derived features for ALS-versus-control classification

Compact longitudinal representations derived f...

Bioinformatics
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librarian
3 views
Computational Design and Atomistic Validation of a High-Affinity VHH Nanobody Targeting the PI/RuvC Interface of Streptococcus pyogenes Cas9: A Bivalent Hub Strategy for CRISPR-Cas9 Enhancement

Computational Design and Atomistic Validation ...

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librarian
3 views
AI-guided design of candidate BMPR1A-binding peptides for cartilage regeneration: a multi-tool computational benchmarking study

AI-guided design of candidate BMPR1A-binding p...

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librarian
3 views
STRmie-HD enables interruption-aware HTT repeat genotyping and somatic mosaicism profiling across sequencing platforms

STRmie-HD enables interruption-aware HTT repea...

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Alessandro Napoli
2 views
From SNPs to Pathways: A genome-wide benchmark of annotation discrepancies and their impact on protein- and pathway-level inference

From SNPs to Pathways: A genome-wide benchmark...

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librarian
3 views
dreampy: Pseudobulk mixed-model differential expression for single-cell RNA-seq in Python

dreampy: Pseudobulk mixed-model differential e...

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librarian
3 views
PACMON: Pathway-guided Multi-Omics data integration for interpreting large-scale perturbation screens

PACMON: Pathway-guided Multi-Omics data integr...

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Florian Buettner
1 view
MiCBuS: Marker Gene Mining for Unknown Cell Types Using Bulk and Single Cell RNA-Seq Data

MiCBuS: Marker Gene Mining for Unknown Cell Ty...

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Shanshan Zhang
1 view
Col-Ovo: Smartphone-based artificial intelligence for rapid counting of Aedes mosquito eggs under field conditions

Col-Ovo: Smartphone-based artificial intellige...

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Diego Montenegro
4 views
A comprehensive reference database to support untargeted metabolomics in Pseuudomonas putida

A comprehensive reference database to support ...

Bioinformatics
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Jessica Bade
3 views
VPF-Class 2.0: a taxonomy-centered framework for automatic viral classification

VPF-Class 2.0: a taxonomy-centered framework f...

Bioinformatics
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librarian
6 views
Single-cell Landscape of T Cell Heterogeneity in Kawasaki Disease: STAT3/JAK Axis Regulates the Lineage Differentiation Bias of Th17 Cells

Single-cell Landscape of T Cell Heterogeneity ...

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Sirui Song
7 views
TogoMCP: Natural Language Querying of Life-Science Knowledge Graphs via Schema-Guided LLMs and the Model Context Protocol

TogoMCP: Natural Language Querying of Life-Sci...

Bioinformatics
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librarian
9 views
Rastair: an integrated variant and methylation caller

Rastair: an integrated variant and methylation...

Bioinformatics
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Benjamin Schuster-Boeckler
11 views
The Risk of Gulf Birds Functional Diversity Loss with Climate Change Uncovered Using Deep Learning Population Models

The Risk of Gulf Birds Functional Diversity Lo...

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Liying Li
9 views
EvoMut: A Computational Framework for Engineering Oxidative Stability in Proteins

EvoMut: A Computational Framework for Engineer...

Bioinformatics
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Seyed Shahriar Arab
7 views
Solving the Diagnostic Odyssey with Synthetic Phenotype Data

Solving the Diagnostic Odyssey with Synthetic ...

Bioinformatics
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Gianlucca Colangelo
7 views
A harmonized benchmarking framework for implementation-aware evaluation of 46 polygenic risk score tools across binary and continuous phenotypes

A harmonized benchmarking framework for implem...

Bioinformatics
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librarian
8 views
Helicase: Vectorized parsing and bitpacking of genomic sequences

Helicase: Vectorized parsing and bitpacking of...

Bioinformatics
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librarian
16 views
Long-read metagenomic sequencing reveals novel lineages and functional diversity in urban soil microbiome

Long-read metagenomic sequencing reveals novel...

Bioinformatics
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librarian
16 views
PanXpress: Gene expression quantification with a pan-transcriptomic gapped k-mer index

PanXpress: Gene expression quantification with...

Bioinformatics
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librarian
29 views
Improving genomic language model reliability under distribution shift

Improving genomic language model reliability u...

Bioinformatics
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Gavin Hearne
19 views
Differentiable Gene Set Enrichment Analysis for Pathway-Level Supervision in Transcriptomic Learning

Differentiable Gene Set Enrichment Analysis fo...

Bioinformatics
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librarian
20 views
Disagreement among variant effect predictors guides experimental prioritization of target proteins

Disagreement among variant effect predictors g...

Bioinformatics
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librarian
17 views
Mapping spatial cell-cell communication programs by tailoring chains of cells for transformer neural networks

Mapping spatial cell-cell communication progra...

Bioinformatics
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Niklas Brunn
21 views
RNASTOP: A Deep Learning Framework for mRNA Chemical Stability Prediction and Optimization

RNASTOP: A Deep Learning Framework for mRNA Ch...

Bioinformatics
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librarian
30 views
Computational Prediction of Plasmodium falciparum Antigen-T-cell Receptor Interactions via Molecular Docking: Implications for Malaria Vaccine Design

Computational Prediction of Plasmodium falcipa...

Bioinformatics
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Gilbert Kipkoech
20 views
RNAGAN: Train One and Get Four, Multipurpose Human RNA-Seq Analysis Tool with Enhanced Interpretability and Small Data Size Capability

RNAGAN: Train One and Get Four, Multipurpose H...

Bioinformatics
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librarian
16 views
ECHO: a nanopore sequencing-based workflow for (epi)genetic profiling of the human repeatome

ECHO: a nanopore sequencing-based workflow for...

Bioinformatics
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librarian
24 views
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