Cancer Biology

Relapse-founding cancer persister cells in follicular lymphoma

Relapse-founding cancer persister cells in fol...

Cancer Biology
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librarian
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Defining biologically directed therapy target signatures in urothelial carcinoma: A transcriptomic framework for precision therapy

Defining biologically directed therapy target ...

Cancer Biology
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librarian
2 views
Therapy-Induced Clonal Selection as a Driver of Response to JAK Inhibitors in Myelofibrosis

Therapy-Induced Clonal Selection as a Driver o...

Cancer Biology
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librarian
2 views
Stromal Prostaglandin is a Dominant Spatial Regulator of Cell-fate Plasticity in Colorectal Cancer

Stromal Prostaglandin is a Dominant Spatial Re...

Cancer Biology
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Corinne Molyneux
3 views
Hypoxia-activated prodrug and chemotherapy disrupt resistance-associated metabolism in osteosarcoma

Hypoxia-activated prodrug and chemotherapy dis...

Cancer Biology
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Laura Cole
3 views
Dihydropyrimidines sustain aggressive cancer states by stabilizing DPYSL2

Dihydropyrimidines sustain aggressive cancer s...

Cancer Biology
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Yoav Shaul
3 views
Oncohistone inhibition reshapes tumor-microenvironment communication in Diffuse Midline Glioma (DMG)

Oncohistone inhibition reshapes tumor-microenv...

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librarian
3 views
Albumin-coated VS1 nanocrystals enable STARD3 inhibition and potentiate fluoropyrimidine therapy in colorectal cancer

Albumin-coated VS1 nanocrystals enable STARD3 ...

Cancer Biology
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Flavio Rizzolio
3 views
Elongin B orchestrates chromatin and transcriptional programs in H3K27M-mutant diffuse midline glioma

Elongin B orchestrates chromatin and transcrip...

Cancer Biology
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librarian
111 views
Tumoral Switch in NUMB splicing changes essential transcription pathways and induces malignant properties in tumour cells

Tumoral Switch in NUMB splicing changes essent...

Cancer Biology
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librarian
111 views
β-Hydroxybutyrate elicits divergent metabolic responses between MCF-7 and T47D ER+ breast cancer cells under glucose restriction

β-Hydroxybutyrate elicits divergent metabolic ...

Cancer Biology
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Michael Weichhaus
101 views
MYC overexpression drives poor prognosis and differential sensitivity to treatments according to TP53 status in chronic lymphocytic leukemia

MYC overexpression drives poor prognosis and d...

Cancer Biology
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María Hernández-Sánchez
94 views
Cellular stemness identifies high-risk ductal carcinoma in situ and offers a therapeutic interception opportunity

Cellular stemness identifies high-risk ductal ...

Cancer Biology
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librarian
105 views
Neutral Sphingomyelinase-2 Restrains TAZ to Suppress Breast Tumor Growth

Neutral Sphingomyelinase-2 Restrains TAZ to Su...

Cancer Biology
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librarian
114 views
LVV SMRTcap reveals extensive proviral variation in lentiviral vector-transduced CAR T cells

LVV SMRTcap reveals extensive proviral variati...

Cancer Biology
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librarian
97 views
Genomic, Clinical, and Spatial Predictors of Durable Response to BRAF/MEK Inhibition in BRAF-Mutant Melanoma

Genomic, Clinical, and Spatial Predictors of D...

Cancer Biology
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librarian
97 views
Purinergic signaling promotes gliomagenesis through nuclear calcium transients

Purinergic signaling promotes gliomagenesis th...

Cancer Biology
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librarian
96 views
Glutamatergic neuron-tumor synapses shape human glioblastoma cell states through radial glia plasticity

Glutamatergic neuron-tumor synapses shape huma...

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librarian
102 views
Cell line-dependent effects of spheroid formation method on drug response in melanoma models

Cell line-dependent effects of spheroid format...

Cancer Biology
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Akvilė Žilytė
111 views
Integrated spatial and single-cell transcriptomic analysis of aggressive glioblastoma growth dynamics.

Integrated spatial and single-cell transcripto...

Cancer Biology
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librarian
103 views
Compact serum miRNA qPCR model for pancreatic cancer discrimination with independent and clinical validation

Compact serum miRNA qPCR model for pancreatic ...

Cancer Biology
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Yoshitake Sano
106 views
FASN Inhibition Resensitizes Chordoma to Radiotherapy by Targeting Adaptive Unsaturated Fatty Acid Metabolism

FASN Inhibition Resensitizes Chordoma to Radio...

Cancer Biology
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librarian
102 views
Integrated Collagen Architecture and Composition Improve Risk Stratification in Triple-Negative Breast Cancer

Integrated Collagen Architecture and Compositi...

Cancer Biology
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librarian
96 views
Functional T cells trapped behind a stromal wall: a Brake-with-Wall phenotype redefines pancreatic adenocarcinoma immunotherapy resistance

Functional T cells trapped behind a stromal wa...

Cancer Biology
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Jeong-Soon Yong
232 views
The miR-221-5p/RAD18/RAD51 axis regulates DNA damage tolerance and homologous recombination to drive platinum resistance in ovarian cancer.

The miR-221-5p/RAD18/RAD51 axis regulates DNA ...

Cancer Biology
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Komaraiah Palle
95 views
The CNS-penetrant MAP4K inhibitor famlasertib restrains medulloblastoma dissemination without developmental toxicity

The CNS-penetrant MAP4K inhibitor famlasertib ...

Cancer Biology
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librarian
100 views
Ablation of glypican-3 enhances radiosensitivity in liver cancer by prolonging G2/M arrest and activating the ATM/CHK2 pathway

Ablation of glypican-3 enhances radiosensitivi...

Cancer Biology
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Joon-Yong Chung
144 views
Profilin-1 Promotes Chromophobe Renal Cell Carcinoma Malignancy

Profilin-1 Promotes Chromophobe Renal Cell Car...

Cancer Biology
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librarian
89 views
TumorArchetypeR: A modular framework to derive signature-based tumor subtypes

TumorArchetypeR: A modular framework to derive...

Cancer Biology
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librarian
97 views
Collective cancer cell calcium activity drives brain metastasis

Collective cancer cell calcium activity drives...

Cancer Biology
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librarian
103 views
Neuroendocrine-like/EMT dedifferentiation mediates resistance to EGFR inhibitors via the NRG1/HER3 axis

Neuroendocrine-like/EMT dedifferentiation medi...

Cancer Biology
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Mattia Lauriola
99 views
SOCS1 expression in prostate epithelial cells is essential for tissue homeostasis and tumor suppression

SOCS1 expression in prostate epithelial cells ...

Cancer Biology
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librarian
98 views
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