Cancer Biology

Organoid modeling of tumor-associated macrophages reveals phagocytosis checkpoint blockade-induced conversion to an immunosuppressive SPP1+ phenotype

Organoid modeling of tumor-associated macropha...

Cancer Biology
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librarian
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Ecological determinants of disease and immunity in myelodysplastic syndromes

Ecological determinants of disease and immunit...

Cancer Biology
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librarian
2 views
Hypoxia drives trastuzumab resistance through Rac1 pathway in HER2-positive breast cancer

Hypoxia drives trastuzumab resistance through ...

Cancer Biology
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librarian
3 views
Beyond Capture Efficiency: A Multidimensional Framework for Benchmarking Circulating Tumor Cell Isolation Technologies

Beyond Capture Efficiency: A Multidimensional ...

Cancer Biology
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librarian
3 views
TUMOR-PRE-ADIPOCYTE CROSSTALK SUSTAINS BREAST CANCER GROWTH VIA RET SIGNALLING

TUMOR-PRE-ADIPOCYTE CROSSTALK SUSTAINS BREAST ...

Cancer Biology
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librarian
2 views
Conserved principles of central carbon partitioning in Hippo-Yorkie-driven Drosophila gut tumors

Conserved principles of central carbon partiti...

Cancer Biology
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Younshim Park
3 views
KRAS-Mediated CCDC6 Degradation Drives xCT Upregulation and Ferroptosis Evasion

KRAS-Mediated CCDC6 Degradation Drives xCT Upr...

Cancer Biology
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Angela Celetti
3 views
Improve the Efficacy of B7-H3-Targeting Antibody-Drug Conjugate DS-7300a in TP53-deficient Tumors by Inducing Ferroptosis

Improve the Efficacy of B7-H3-Targeting Antibo...

Cancer Biology
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Di Zhao
4 views
Ligand stabilization enables physiological GITR signaling and antitumor immunity

Ligand stabilization enables physiological GIT...

Cancer Biology
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Murali Ramachandran
6 views
Loss of PGC1α drives extracellular matrix remodelling in prostate cancer through CTHRC1

Loss of PGC1α drives extracellular matrix remo...

Cancer Biology
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librarian
4 views
Cancer Evolvability Determines Therapy Outcomes

Cancer Evolvability Determines Therapy Outcomes

Cancer Biology
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Ranjini Bhattacharya
4 views
CMS4-focused multi-omic integration enhances antigen target identification in colorectal cancer

CMS4-focused multi-omic integration enhances a...

Cancer Biology
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librarian
6 views
CXCL13-CXCR5 Signaling in CD8⁺ T Cell Recruitment and Lymphoid Immune Organization in Clear Cell Renal Cell Carcinoma

CXCL13-CXCR5 Signaling in CD8⁺ T Cell Recruitm...

Cancer Biology
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librarian
7 views
A Single-Cell Peripheral Immune Atlas Spanning High-Risk Lesions to Invasive Breast Cancer in Black and White Women

A Single-Cell Peripheral Immune Atlas Spanning...

Cancer Biology
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Elizabeth Mittendorf
8 views
Enteric neurons modulate colorectal cancer cell cycle through a PCSK1 - Methionine-Enkephalin Axis

Enteric neurons modulate colorectal cancer cel...

Cancer Biology
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librarian
10 views
Multispecific nanobody degraders co-deplete membrane receptors and enable targeted delivery of diverse payloads

Multispecific nanobody degraders co-deplete me...

Cancer Biology
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Md Kabir
11 views
hTERT Expression, Regulation, and Prognostic Significance in Pediatric Medulloblastoma

hTERT Expression, Regulation, and Prognostic S...

Cancer Biology
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Rachid Drissi
15 views
Integrating spatial and single-cell multi-omics analysis of induced pluripotent stem cell-derived cervical adenocarcinoma model

Integrating spatial and single-cell multi-omic...

Cancer Biology
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Ayumi Taguchi
10 views
Phosphoglycerate mutase 5 regulates lipid metabolism and mitochondrial homeostasis in hepatocellular cancer cells

Phosphoglycerate mutase 5 regulates lipid meta...

Cancer Biology
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librarian
9 views
Stromal Gasdermin D-mediated Pyroptosis Drives Maladaptive CD4⁺ T-cell Remodeling in Tet2-Deficient Hematopoiesis

Stromal Gasdermin D-mediated Pyroptosis Drives...

Cancer Biology
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librarian
9 views
CPT1A loss promotes lung metastasis in immune-competent mice via a mechanism of mtDNA release and chronic activation of STING pathway

CPT1A loss promotes lung metastasis in immune-...

Cancer Biology
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Deanna Edwards
11 views
Contrast-induced changes in chemical exchange saturation transfer MRI differentiate tumor progression from pseudoprogression

Contrast-induced changes in chemical exchange ...

Cancer Biology
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Mohammad Haris
7 views
Multi-omics analysis reveals integrin α3-dependent mechanisms of Zika virus oncolytic activity in pediatric neural tumor

Multi-omics analysis reveals integrin α3-depen...

Cancer Biology
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librarian
16 views
Fluid shear stress modulates endocytic pathways and junctional targeting of tumor-derived extracellular vesicles in endothelial cells

Fluid shear stress modulates endocytic pathway...

Cancer Biology
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Vanessa Freitas
13 views
First-in-Class Small Molecules Inhibit c-MET Activity Through Self-Regulatory Elements in Its Extracellular Domain

First-in-Class Small Molecules Inhibit c-MET A...

Cancer Biology
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librarian
13 views
Spatial and Bulk Transcriptomic Profiling Defines the Molecular Evolution of Cutaneous Squamous Cell Carcinoma and Reveals Stage-Specific Biomarkers of Clinical Relevance

Spatial and Bulk Transcriptomic Profiling Defi...

Cancer Biology
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Hamid-Reza Rezvani
12 views
Spatial single-cell proteomics defines multicellular niches in the primary prostate cancer microenvironment

Spatial single-cell proteomics defines multice...

Cancer Biology
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Marianna Rapsomaniki
12 views
Discovery of a Systemic Immune-Inflammatory Axis Bridging the Neuroendocrine System and Breast Tumor Microenvironment via MMD-Regularized Cross-Tissue Latent Alignment

Discovery of a Systemic Immune-Inflammatory Ax...

Cancer Biology
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librarian
20 views
Coordinated immune architecture underlies durable survival in pancreatic cancer

Coordinated immune architecture underlies dura...

Cancer Biology
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librarian
16 views
A generative reference grammar of healthy TCR repertoires reveals cancer-associated immune remodeling

A generative reference grammar of healthy TCR ...

Cancer Biology
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librarian
16 views
Changes in the Transcriptome and Synthetic Lethal Dependencies Following KRAS Mutant Expression Reveal Profound Tissue-Specificity

Changes in the Transcriptome and Synthetic Let...

Cancer Biology
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librarian
19 views
Decoding the BRCA2 reversion principles underlying PARP inhibitor resistance

Decoding the BRCA2 reversion principles underl...

Cancer Biology
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librarian
28 views
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