Cancer Biology

Midkine Dependency Defines a Therapeutically Actionable Vulnerability in Medulloblastoma

Midkine Dependency Defines a Therapeutically A...

Cancer Biology
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Gangadhara Sareddy
3 views
DNA Demethylation is Dispensable for Venetoclax-HMA Synergy in Acute Myeloid Leukaemia

DNA Demethylation is Dispensable for Venetocla...

Cancer Biology
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Sandra Hellberg
5 views
A PSMA-Targeted Up-conversion Nanoplatform for Deep-Tissue dual activation Photodynamic and Sonodynamic Therapy of Castration Resistant Prostate Cancer.

A PSMA-Targeted Up-conversion Nanoplatform for...

Cancer Biology
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Paras Prasad
3 views
Single-cell lineage tracing maps clonal and transcriptional dynamics in melanoma metastasis

Single-cell lineage tracing maps clonal and tr...

Cancer Biology
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librarian
2 views
FUT8 mediated core fucosylation modulates growth related functions of LRP1 in liver cancer cells

FUT8 mediated core fucosylation modulates grow...

Cancer Biology
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Eiji Miyoshi
2 views
ARID1A deficiency unleashes centromeric RNA transcription to drive chromosomal instability and boosts PKMYT1 inhibitor efficacy via RNA sensing

ARID1A deficiency unleashes centromeric RNA tr...

Cancer Biology
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Guang Peng
2 views
PRMT5 as an Epigenetic Target for Group 3 (MYC-driven) Medulloblastoma

PRMT5 as an Epigenetic Target for Group 3 (MYC...

Cancer Biology
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librarian
2 views
Modulation of Oncogenic KRAS Signaling by Branched Actin-driven Cell Membrane Protrusions

Modulation of Oncogenic KRAS Signaling by Bran...

Cancer Biology
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librarian
2 views
Organoids serve as viable in vitro model for functional precision medicine for mesonephric-like adenocarcinoma of the ovary

Organoids serve as viable in vitro model for f...

Cancer Biology
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librarian
2 views
DNA methylation signatures of mismatch repair-deficient colorectal cancer

DNA methylation signatures of mismatch repair-...

Cancer Biology
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librarian
2 views
FOXA1 preserves cell polarity and restrains lysosome biogenesis in non-small cell lung adenocarcinoma

FOXA1 preserves cell polarity and restrains ly...

Cancer Biology
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Jianxing He
10 views
Multi-region biopsies and patient-derived neurosphere cultures reveal spatial divergence in glioblastoma.

Multi-region biopsies and patient-derived neur...

Cancer Biology
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Franziska Michor
7 views
Transcriptomic, Genomic, and Clinical Characterization of Morphological Classes in Localized and Metastatic Pancreatic Cancer

Transcriptomic, Genomic, and Clinical Characte...

Cancer Biology
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librarian
11 views
KRAS inhibition is an effective therapy for appendiceal adenocarcinoma

KRAS inhibition is an effective therapy for ap...

Cancer Biology
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John Shen
13 views
The HPV E7 oncoprotein promotes LIM and SH3 Domain Protein 1 (LASP1) transcription via the Rb/E2F1 signalling pathway in HPV-positive cervical cancer cells

The HPV E7 oncoprotein promotes LIM and SH3 Do...

Cancer Biology
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librarian
9 views
Marker-based CRISPR screens identify POU2F1 as a regulator of DLL3 and neuroendocrine identity in small cell lung cancer

Marker-based CRISPR screens identify POU2F1 as...

Cancer Biology
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librarian
6 views
H3 dopaminylation and CaMKII modulate diffuse midline glioma response to CDK9 inhibition

H3 dopaminylation and CaMKII modulate diffuse ...

Cancer Biology
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librarian
5 views
Nanoparticle-delivered resiquimod induces brain tumor regression in medulloblastoma and diffuse midline glioma models by interrupting paracrine growth support and activating myeloid immune signaling and phagocytosis

Nanoparticle-delivered resiquimod induces brai...

Cancer Biology
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librarian
9 views
Myeloma and therapy reshape the bone marrow niche to durably constrain immune reconstitution and vaccine responsiveness

Myeloma and therapy reshape the bone marrow ni...

Cancer Biology
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librarian
10 views
Expression profile of CASSIOPEIA patients refines prognostic value of MRD negativity in multiple myeloma

Expression profile of CASSIOPEIA patients refi...

Cancer Biology
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librarian
13 views
A SIRT5-induced metabolic switch underlies chemoresistance and ATR checkpoint dependence in triple-negative breast cancer

A SIRT5-induced metabolic switch underlies che...

Cancer Biology
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librarian
12 views
RUNX1-deficiency drives immune-active ER+ mammary tumorigenesis through activation of interferon signaling

RUNX1-deficiency drives immune-active ER+ mamm...

Cancer Biology
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librarian
11 views
Integrating Fas-mediated apoptosis with IFNγ signaling to drive tumor regression in mRNA cancer therapeutics

Integrating Fas-mediated apoptosis with IFNγ s...

Cancer Biology
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librarian
8 views
A Hierarchical Spatial Graph Neural Network Resolves Immunogenic and Tolerogenic Tertiary Lymphoid Structures in Renal Cell Carcinoma

A Hierarchical Spatial Graph Neural Network Re...

Cancer Biology
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librarian
11 views
lncRNA MANCR isoforms selectively mediate multiple levels of epigenomic and P53-responsive transcriptional control in triple negative breast cancer

lncRNA MANCR isoforms selectively mediate mult...

Cancer Biology
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Janet Stein
11 views
Early Epigenetic and Metabolic Responses to the Adipocyte Secretome Reveal Stress-Adaptive States in Triple-Negative Breast Cancer

Early Epigenetic and Metabolic Responses to th...

Cancer Biology
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librarian
10 views
Serial Thermal Ablation Induces Abscopal Antitumor Immunity and Reveals Targetable CSF1R-Dependent Resistance in Pancreatic Cancer

Serial Thermal Ablation Induces Abscopal Antit...

Cancer Biology
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librarian
10 views
Transcription Factor Subtype Governs Response and Resistance to DLL3-Directed T-Cell Engagement in Small Cell Lung Cancer

Transcription Factor Subtype Governs Response ...

Cancer Biology
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librarian
20 views
Distinct Spatial Programs of Response versus Resistance in Non-Small Cell Lung Cancer after Neoadjuvant Chemoimmunotherapy

Distinct Spatial Programs of Response versus R...

Cancer Biology
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librarian
13 views
Defining the RNA Modification Landscape of Multiple Myeloma Reveals METTL3-Dependent m6A Regulation of NEAT1

Defining the RNA Modification Landscape of Mul...

Cancer Biology
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librarian
17 views
NFATC2 in pancreatic cancer-associated fibroblasts predicts treatment response and facilitates ERBB-targeted therapies

NFATC2 in pancreatic cancer-associated fibrobl...

Cancer Biology
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Biswajyoti Sahu
20 views
SPEND-hSRS imaging of fumarate uncovers mitochondrial metabolic heterogeneity

SPEND-hSRS imaging of fumarate uncovers mitoch...

Cancer Biology
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librarian
12 views
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