Molecular Biology

Synovial fibroblast niche shapes the efficacy - safety dynamics of JAK inhibition in rheumatoid arthritis
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Mojca Frank Bertoncelj
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Structural Insights into Bromodomain-Containing Complexes from Trypanosoma cruzi Revealed by Proximity Labeling and Stoichiometric Space Exploration
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Elvio Rodríguez Araya
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Ribonuclease L Regulates Antiviral Responsiveness through Cleavage of XBP1 mRNA
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Yasutoshi Akiyama
7 views
Altered salivary miRNA profiles and microbiome composition correlate with psychosocial stress
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Alessio Naccarati
10 views
Advancing Nuclei Isolation from Frozen Human Heart for Single-Nucleus RNA Sequencing Applications
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Monika Gladka
12 views
Nuclear speckle protein SON safeguards efficient splicing of GC-rich genes
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Yafei Yin
18 views
Insights into tick-pathogen interactions - a single cell RNA sequencing approach of transcriptional changes during ehrlichial infection
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librarian
22 views
HCF1 orchestrates O-GlcNAcylation and affinity-dependent transcription through extended molecular determinants and register-shifted binding
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Mihkel Örd
17 views
Damaging the conical morphology of HIV-1 capsid by targeting the FG-binding pocket and disfavoring pentameric subunits needed for core closure
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librarian
14 views
Pathogenic Leptospira in dogs and rodents in Tha Wang Pha, Thailand - Prevalence, diversity and linked environments
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librarian
22 views
Friedreich ataxia transcriptomic dysregulation and identification of cell type-specific biomarkers: A systematic review and meta-analysis
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Marnie Maddock
13 views
GRASP: A PLANT TRANSFORMATION-INDEPENDENT CRISPR-BASED SYSTEM FOR AFFINITY PURIFICATION OF SPECIFIC CHROMATIN LOCI
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Alessandro Vannozzi
13 views
CRISPR-Cas immune repertoires as an ecological record of bacterial interactions with mobile genetic elements in the human gut
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Ekaterina Avershina
14 views
A Long-Context Generative Foundation Model Deciphers RNA Design Principles
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librarian
34 views
OmniBind: Proteome-Wide Promiscuity Predictions for Early-Stage Drug Screening
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librarian
22 views
APEX1 Protects Cardiomyocytes Against Oxidative Stress by Regulating p53 Protein Stability
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librarian
16 views
A GABARAP-PtdIns3K-C1 positive feedback loop at the heart of the phagophore nucleation
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Roger Williams
14 views
Anticipatory metabolic reprogramming distinguishes caloric restriction from fasting-refeeding cycles
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Roman Kondratov
15 views
FYCO1 improves postischemic cardiac remodeling via enhanced autophagic flux and attenuation of proinflammatory signaling
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Norbert Frey
17 views
Towards molecular-based functional classification of fetal bovine serum
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Lara Magni
17 views
Seminal extracellular vesicles from boar AI doses contain fertility-predictive protein and miRNA cargo and improve sperm physiology
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librarian
13 views
Combination of alpha-synuclein aggregation inhibitor anle138b and ER stress inhibitor AMG PERK 44 increases neuroprotection in Parkinson's disease organoid model
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librarian
17 views
The Genesis Framework: A Systems-Control Architecture for Safe Partial Cellular Rejuvenation via Stoichiometric saRNA Delivery, Integrated miRNA Logic Gating, and SORT Lipid Nanoparticles
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Cesar Cepeda
66 views
Digoxin Inhibits Bax{triangleup}2-induced Neuronal Cell Death
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Jialing Xiang
17 views
Gene transcription and chromatin packing domains form a self-organizing system
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librarian
18 views