Pharmacology and Toxicology

Three nitrogen atoms turn old kinase inhibitors into new targetable remedy

Three nitrogen atoms turn old kinase inhibitor...

Pharmacology and Toxicology
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librarian
2 views
Using Patient iPSC-derived Retinal Pigment Epithelial Cells to Evaluate Differential Susceptibility to MEK Inhibitor-Associated Retinopathy

Using Patient iPSC-derived Retinal Pigment Epi...

Pharmacology and Toxicology
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librarian
4 views
Impact of Sex on Heroin Intravenous Self-Administration by Heterogeneous Stock Rats

Impact of Sex on Heroin Intravenous Self-Admin...

Pharmacology and Toxicology
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librarian
5 views
Influence of different pharmaceuticals on the germination and early development of two leafy vegetable species

Influence of different pharmaceuticals on the ...

Pharmacology and Toxicology
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librarian
4 views
Pinus sp. leaf extracts exert antileishmanial effects against Leishmania donovani by targeting trypanothione reductase

Pinus sp. leaf extracts exert antileishmanial ...

Pharmacology and Toxicology
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librarian
7 views
PROTAC internalization and target degradation require clathrin-mediatedendocytosis

PROTAC internalization and target degradation ...

Pharmacology and Toxicology
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Hong-Yu Li
11 views
Morphological and Functional Effects of Cytoskeletal and Ion-Channel Agents on the Protoscolex of Echinococcus granulosus sensu lato

Morphological and Functional Effects of Cytosk...

Pharmacology and Toxicology
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librarian
12 views
Simian Immunodeficiency Virus and Antiretroviral Therapy Impact Rhesus Macaque Brain Lipid Distribution

Simian Immunodeficiency Virus and Antiretrovir...

Pharmacology and Toxicology
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librarian
19 views
Changes in dysbiosis and gene expression in the gut of wharf roach (Ligia Spp.) fed with expanded polystyrene

Changes in dysbiosis and gene expression in th...

Pharmacology and Toxicology
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Seokhyun Lee
19 views
Low cadmium concentrations alter B and T cell responses in Jamaican fruit bats (Artibeus jamaicensis)

Low cadmium concentrations alter B and T cell ...

Pharmacology and Toxicology
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Laura Pulscher
13 views
Nicotine self-administration increases impulsive action: differential effects of nAChR modulators in a Go/No-Go task

Nicotine self-administration increases impulsi...

Pharmacology and Toxicology
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librarian
18 views
In vivo pharmacokinetics and tissue distribution profile of a Wnt/β-catenin pathway-targeting anticancer cassane diterpene isolated from Caesalpinia pulcherrima

In vivo pharmacokinetics and tissue distributi...

Pharmacology and Toxicology
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librarian
25 views
Steroid-based Tide Quencher 1 probes enable real-time mapping of novel non-canonical cholesterol sites on the M1 muscarinic receptor

Steroid-based Tide Quencher 1 probes enable re...

Pharmacology and Toxicology
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librarian
24 views
Cirrina: LLM-driven pharmacological reasoning agent enables preclinical CNS drug evaluation

Cirrina: LLM-driven pharmacological reasoning ...

Pharmacology and Toxicology
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librarian
18 views
Study comparing characteristics of ademetionine-containing tablets from different countries

Study comparing characteristics of ademetionin...

Pharmacology and Toxicology
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Azadeh Safaei
24 views
Comparative chemical characterisation of chitosans and their impact on growth, faecal consistency and microbiota composition in weaned piglets

Comparative chemical characterisation of chito...

Pharmacology and Toxicology
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Simona Di Blasio
22 views
Apelin inhibits cyst growth and improves kidney function in mice with polycystic kidney disease

Apelin inhibits cyst growth and improves kidne...

Pharmacology and Toxicology
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librarian
20 views
A stapled peptide inhibitor of MDM2 enables pharmacological activation of p53 in zebrafish

A stapled peptide inhibitor of MDM2 enables ph...

Pharmacology and Toxicology
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Dilraj Lama
19 views
AI-Enforced Ultra-Large Virtual Screening Discovers Potent CD28 Binders

AI-Enforced Ultra-Large Virtual Screening Disc...

Pharmacology and Toxicology
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librarian
23 views
INVESTIGATION OF ETHYLENE OXIDE GENOTOXICITY DOSE-RESPONSE TO INFORM CANCER RISK ASSESSMENT

INVESTIGATION OF ETHYLENE OXIDE GENOTOXICITY D...

Pharmacology and Toxicology
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Abby Li
22 views
Molecular Dosimetry of DNA Adducts in Mice Exposed to Ethylene Oxide

Molecular Dosimetry of DNA Adducts in Mice Exp...

Pharmacology and Toxicology
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Kun Lu
29 views
An optimized protocol for single-brain isolation of sex-defined pure mouse astrocyte cultures

An optimized protocol for single-brain isolati...

Pharmacology and Toxicology
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librarian
20 views
Integrated evaluation of immune system perturbation using structural, functional and cellular immunotoxicity endpoints in rats

Integrated evaluation of immune system perturb...

Pharmacology and Toxicology
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Vinay Lomash
28 views
Transporter-Mediated Uptake of Microcystin-LR in Human Trophoblasts: Regulation By Oxygen Concentration and Cell Fusion

Transporter-Mediated Uptake of Microcystin-LR ...

Pharmacology and Toxicology
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librarian
22 views
In vitro investigation and evaluation of the antidiabetic potential of the ethanolic extract of Asparagus racemosus using starch digestion, glucose diffusion, glucose uptake, and DPPH assays

In vitro investigation and evaluation of the a...

Pharmacology and Toxicology
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Md. Sifat Rahman
21 views
Microencapsulated Vaccinium floribundum Kunth extract promotes angiogenesis and attenuates inflammation in in vitro and in vivo models.

Microencapsulated Vaccinium floribundum Kunth ...

Pharmacology and Toxicology
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Giulia Biondolillo
19 views
Investigating the nicotinic receptor EAT-2 as a novel target to mitigate plant parasitic nematode infections

Investigating the nicotinic receptor EAT-2 as ...

Pharmacology and Toxicology
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Henry Nvenankeng
24 views
Effects of polystyrene and polylactide nanoparticles on macrophages under a repeated exposure mode

Effects of polystyrene and polylactide nanopar...

Pharmacology and Toxicology
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librarian
27 views
Anti-oxidant and anti-inflammatory Effects of Aerosolised microalgal-derived extracellular vesicles in Bronchial Epithelial-Macrophage Co-cultures at the Air-Liquid Interface

Anti-oxidant and anti-inflammatory Effects of ...

Pharmacology and Toxicology
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librarian
24 views
BODIPY-Tagged β-Lactams as Selective Quenched Activity-Based Probes to Target Human Neutrophil Elastase

BODIPY-Tagged β-Lactams as Selective Quenched ...

Pharmacology and Toxicology
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librarian
24 views
Molecular Determinants Governing the Antitubercular Activity of Griselimycin

Molecular Determinants Governing the Antituber...

Pharmacology and Toxicology
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Andrew Spira
27 views
Efficacy of SGLT2 Inhibitors in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis of Preclinical Studies

Efficacy of SGLT2 Inhibitors in Pulmonary Arte...

Pharmacology and Toxicology
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librarian
27 views
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