Synthetic Biology

Humanized Caffeine-Inducible Systems for Controlling Cellular Functions
Avatar
Leo Scheller
8 views
Treating Myotonic Dystrophy with artificial RNA endonucleases to specifically degrade toxic RNA expansions
Avatar
librarian
10 views
Phage-Assisted Evolution of Allosteric Protein Switches
Avatar
librarian
17 views
Heterologous expression of microbial nitroreductases for TNT degradation in transgenic animals
Avatar
librarian
30 views
A DNA part library for reliable engineering of the emerging model nematode symbiotic bacterium Xenorhabdus griffiniae HGB2511
Avatar
Elin Larsson
41 views
Engineering lung-sensing T cells using synthetic receptors targeting RAGE
Avatar
librarian
63 views
Single-cell characterization of bacterial optogenetic Cre recombinases
Avatar
librarian
62 views
Tuning viscoelasticity and fine structure of living materials via synthetic adhesion logic and rheological perturbations
Avatar
librarian
83 views
Cell-free genome-wide transcriptomics through machine learning optimization
Avatar
librarian
82 views
DNA framework array enables ultra-high throughput DNA synthesis
Avatar
librarian
102 views
Unified Genomic and Chemical Representations Enable Bidirectional Bio-synthetic Gene Cluster and Natural Product Retrieval
Avatar
Chuan Sheng Foo
106 views
Carbon-Efficient Conversion through Hydrogen and Formate-Driven Metabolism in Escherichia coli
Avatar
Jay Keasling
106 views
DNA Flipping as Facile Mechanism for Transmembrane Signaling in Synthetic Cells
Avatar
Lorena Pellejero
106 views
Changing the initiation unit of nonribosomal peptide synthetases to access underexplored biosynthetic potential
Avatar
Xiaoying Bian
105 views
De novo design of hundreds of functional GPCR-targeting antibodies enabled by scaling test-time compute
Avatar
librarian
106 views
Making deep mutational scanning accessible: a cost-efficient approach to construct barcoded libraries for genes of any length
Avatar
librarian
106 views
Characterization of recombinase-based genetic parts and circuits using nanopore sequencing
Avatar
librarian
106 views
Using domain insertion to create sulfite reductases that present chemical-dependent activities
Avatar
librarian
105 views
Orchestrating Self-Replication in Artificial Cells through Digital Microfluidics
Avatar
Mark Wallace
106 views
When good guides go bad: empirical evaluation of all unique Cas9 targets in E. coli reveal widespread functionality and rules for gRNA biological design
Avatar
librarian
106 views
Combinatorial mutagenesis of N-terminal sequences reveals unexpected and expanded stability determinants of the Escherichia coli N-degron pathway
Avatar
librarian
106 views
Peptide Barcodes for miRNA activity assessment in mammalian cells
Avatar
librarian
107 views
Integration of strain and process optimization to increase autotrophic growth of engineered Komagataella phaffii
Avatar
librarian
107 views
Unveiling the hidden window of prime editing
Avatar
librarian
108 views
PYEAST - Python Enabled Automated Strain Transformaiton
Avatar
Carol Hartley
110 views
Multiobjective learning and design of bacteriophage specificity
Avatar
librarian
109 views
Experimental Evaluation of AI-Driven Protein Design Risks Using Safe Biological Proxies
Avatar
Geoffrey Taghon
118 views
Engineered Acinetobacter baylyi ADP1-ISx cells are sensitive DNA biosensors for antibiotic resistance genes and a fungal pathogen of bats
Avatar
librarian
109 views
Sequestration-Based Neural Networks That Operate Out of Equilibrium
Avatar
librarian
111 views
A Saccharomyces boulardii synthetic biotic platform for delivery of therapeutic nanobodies to ameliorate gastrointestinal inflammation
Avatar
librarian
117 views