Synthetic Biology

Model-guided design of single-cargo, dual-attractor gene circuits
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librarian
14 views
SYNBRIDGE: A VERSATILE FRAMEWORK FOR BIDIRECTIONAL INTERCONVERSION BETWEEN BIOBRICKS AND GOLDEN GATE ASSEMBLY STANDARDS
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Manuel Bernal
15 views
PiggyBac transposon and transposase delivered in trans, in cis, and as mRNA for engineering CAR-T cells: a multi-objective optimization
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librarian
21 views
Selective Recognition, Covalent Linkage and Chemical Exchange of Artificial Cells through Engineered α-Hemolysin
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librarian
30 views
Programming Targeted Immune Cell Migration Using Orthogonal Chemokine-Receptor Pairs
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librarian
33 views
Metabolic engineering of Escherichia coli to modulate hydrogen sulfide levels in the mammalian gut
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librarian
180 views
Automated design of stiffness-tunable DNA origami hollowframes for self-assembling metamaterials
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Rebecca Taylor
208 views
Tailoring Precise Genomic Integration Toward Isolate-to-Industry Strain Development for Scalable High-Titer Production of Polyhydroxyalkanoate
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librarian
186 views
Division of Synthetic Cells Using a Genomically Encoded One-Protein Divisome
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librarian
177 views
Continuous target-specific mutagenesis and rapid gene evolution by diversity-generating retroelements in Escherichia coli
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Yang Liu
182 views
Seven mutations unlock strict synthetic methylotrophy in engineered Pseudomonas putida
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Òscar Puiggené
204 views
Programming the Internal Architecture of Synthetic Compartments by Coassembling Filamentous and Liquid DNA Phases
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librarian
187 views
Polymerase Evolution Enables Access to Glycosylated Xeno-Nucleic Acids with Expanded Chemical Functionality
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librarian
209 views
Continuous site-directed mutagenesis and selection in Escherichia coli
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Fabian Rehm
189 views
Hexadecimal data encryption in paranemic crossover (PX) DNA
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librarian
213 views
Synthesis of Ultra-Large Fibrous Proteins from Bacteria via a Looped-Translation System
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librarian
175 views
Pharmacologically regulated bioorthogonal stabilization domain for regulation of CAR T cells
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librarian
194 views
Overcoming protocatechuate and catechol accumulation in muconic acid production via adaptive laboratory evolution and metabolic engineering in Pseudomonas putida
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Alissa Bleem
199 views
Engineered Pseudomonas putida reconfigures metabolic fluxes to support energy demands during muconate bioproduction from lignin-related aromatics
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Allison Werner
206 views
Storing >1 byte of information in 16S ribosomal RNA using orthogonal trans-splicing ribozymes
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librarian
228 views
Pathway selection for arabinose utilization in Pseudomonas putida reveals a rate-yield tradeoff in muconic acid production from lignocellulosic sugars
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Davinia Salvachúa
201 views
Biocontainment attenuation of mobile DNA host range in a wastewater microbiome
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librarian
212 views
Minimal Data, Maximal Insight (MDMI): A Structure-guided Pipeline for Discovering Functional Alternatives in Peptide-Protein Interfaces
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Keith Pardee
192 views
Programmable and Dynamic DNA Localisation at Synthetic Cell Membranes
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librarian
203 views
A microbial growth-coupled platform for in vivo interrogation of Rubisco oxygenase activity
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Enrico Orsi
206 views
BxbI-mediated insertion of a 77kb human RET sensitive haplotype into the mouse genome to generate a humanized model of Hirschsprung disease
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librarian
196 views
Extracellular injection system combined with peptides for intracellular Staphylococcus aureus treatment
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Ningning Song
197 views
MozClo: An Expanded MoClo Toolset for Large Multigene Assembly and Plant Transformations
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Cory Tobin
214 views
Transcription-induced coacervation accelerates and sensitizes cell-free biosensing
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Samanvaya Srivastava
204 views
AAV delivered lysosome-targeting chimeras mediate sustained antibody depletion in vivo
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librarian
204 views
Fabrication and Use of a 32-Well LED-Embedded Microplate for Optogenetic Dynamic Control
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librarian
192 views
Deoxyribonucleotide incorporation reshapes mRNA design beyond canonical ribonucleotide boundaries
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Joseph Rosenecker
203 views