Systems Biology

Insulin Signaling Functions as a Topological Switch That Couples Aging and Heat Stress Responsiveness

Insulin Signaling Functions as a Topological S...

Systems Biology
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librarian
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Cellular Stress Tolerance Governs Genetic Transformability in Recalcitrant Candida Species

Cellular Stress Tolerance Governs Genetic Tran...

Systems Biology
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librarian
1 view
Decoding Spatial Programs in Human Glioblastoma Through Surprisal Information-Theoretical Analysis

Decoding Spatial Programs in Human Glioblastom...

Systems Biology
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librarian
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Stress-Related Transcriptional Regulators Dominate the Conserved Core GRN for Three Cyanobacteria: Network Topology Maps the Highest-Influence Nodes as Promising Engineering Targets

Stress-Related Transcriptional Regulators Domi...

Systems Biology
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librarian
4 views
Differences between suspended and sinking particles regulate carbon flux in the upper mesopelagic during a Phaeocystis Bloom

Differences between suspended and sinking part...

Systems Biology
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Carolina Cisternas-Novoa
2 views
Co-expression network analysis reveals repression of Igf2bp2 by REV-ERBβ in skeletal muscle

Co-expression network analysis reveals repress...

Systems Biology
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librarian
85 views
Coarse-graining metabolic networks via feature learning reveals cross-species growth laws

Coarse-graining metabolic networks via feature...

Systems Biology
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librarian
79 views
Simultaneous single-cell profiling of the transcriptome and proteome

Simultaneous single-cell profiling of the tran...

Systems Biology
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Alex de Marco
80 views
Protein Stability, Turnover Kinetics, and Abundance Constrain the Scaling of Protein Interaction Networks

Protein Stability, Turnover Kinetics, and Abun...

Systems Biology
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librarian
87 views
Global quantification of mammalian gene expression noise

Global quantification of mammalian gene expres...

Systems Biology
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librarian
97 views
MechAInistic: An LLM-guided Multi-Agent System for Reasoning over Genome-Scale Constraint-Based Metabolic Models

MechAInistic: An LLM-guided Multi-Agent System...

Systems Biology
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Josh Loecker
117 views
Uncertainty-aware graph representation learning with positive-unlabeled classification for biomarker discovery in peripheral artery disease

Uncertainty-aware graph representation learnin...

Systems Biology
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Venkat Ayyalasomayajula
86 views
Efficient Bayesian inference for ordinary differential equation models from experimental data with uncertain measurement times

Efficient Bayesian inference for ordinary diff...

Systems Biology
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librarian
82 views
A multiomic lifespan signature in genetically diverse, diet-restricted mice

A multiomic lifespan signature in genetically ...

Systems Biology
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librarian
102 views
Spatially resolved transcriptomic and proteomic profiling reveals cell interaction programs that predict Barrett's esophagus progression

Spatially resolved transcriptomic and proteomi...

Systems Biology
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librarian
93 views
Susagi: A Microbiome World Model

Susagi: A Microbiome World Model

Systems Biology
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librarian
110 views
Homeostatic feedback model of energy metabolism with adaptive enzyme levels exhibits problem solving behavior

Homeostatic feedback model of energy metabolis...

Systems Biology
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Michael Levin
95 views
Talk2QSP: Deriving Executable Scenarios from Unstructured Literature via Human-in-the-Loop Agents

Talk2QSP: Deriving Executable Scenarios from U...

Systems Biology
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librarian
82 views
Learning activator-inhibitor dynamics at the cell cortex with neural likelihood ratio estimation

Learning activator-inhibitor dynamics at the c...

Systems Biology
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Ondrej Maxian
97 views
Systemic stress states are reversed by NPBWR1 inhibition

Systemic stress states are reversed by NPBWR1 ...

Systems Biology
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librarian
95 views
Unraveling the metabolic interactions of a Dehalobacter-containinganaerobic mixed culture for bioremediation

Unraveling the metabolic interactions of a Deh...

Systems Biology
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librarian
93 views
Scalable longitudinal imaging and transcriptomics of cells in dynamic enclosures

Scalable longitudinal imaging and transcriptom...

Systems Biology
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Mostafa Ronaghi
114 views
Mathematical Modeling of the Canonical Aryl Hydrocarbon Receptor Pathway

Mathematical Modeling of the Canonical Aryl Hy...

Systems Biology
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librarian
87 views
Ensemble kinetic modelling links residual enzyme activity to clinical symptoms in mitochondrial β-oxidation defects

Ensemble kinetic modelling links residual enzy...

Systems Biology
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librarian
97 views
A unified framework links infant vulnerability with aging-related mortality dynamics

A unified framework links infant vulnerability...

Systems Biology
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librarian
91 views
COCOA.jl: A Julia package for high-performance analysis of concordance and kinetic modules in biochemical networks

COCOA.jl: A Julia package for high-performance...

Systems Biology
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librarian
91 views
Robotic perturbation proteomics and AI agents enable scalable drug mechanism discovery

Robotic perturbation proteomics and AI agents ...

Systems Biology
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Yuming Jiang
122 views
Multi-omic analysis identifies mitochondrial dysfunction as a conserved driver of acute severity and long-term complications in RSV infection

Multi-omic analysis identifies mitochondrial d...

Systems Biology
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librarian
97 views
Bion-M 2 Biosatellite: Multisystem Mouse Responses to 30 Days in High-Latitude Orbit as a Deep-Space Analog

Bion-M 2 Biosatellite: Multisystem Mouse Respo...

Systems Biology
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librarian
101 views
Box-Counting Fractal Dimensions of Cranial Suture: Effects of Measurement Conditions and Model-Based Reproduction of Fractal-Like Patterns

Box-Counting Fractal Dimensions of Cranial Sut...

Systems Biology
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Takashi Miura
90 views
Lineage-specific lncRNAs critically determine cross-species differences in tumors

Lineage-specific lncRNAs critically determine ...

Systems Biology
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librarian
96 views
REDUCED-PRECISION STOCHASTIC SIMULATION FOR MATHEMATICAL BIOLOGY

REDUCED-PRECISION STOCHASTIC SIMULATION FOR MA...

Systems Biology
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librarian
91 views
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